Combining linear dichroism with a disposable cartridge and instrument.

Our patented technology has a number of distinct advantages in that, not only does it provide very rapid, accurate results, but can measure multiple targets simultaneously in the same sample. Linear dichroism works by detecting a shift in the plane of polarised light when a target is bound to a detector.

A key attribute of this technology is that it can measure multiple targets in the same sample by labelling each detector molecule with a different coloured dye.

Different molecular recognition methods can be used on the detector molecules to measure the target analytes of interest. Antibodies can be used to detect antigens or oligonucleotides to capture complimentary target DNA sequences.

The use of dyes for multiplexing which absorb in the visible region of the light spectrum has enabled Linear Diagnostics to use inexpensive optical components and miniaturise the instrument down to a size where it is fully portable. The system can be run from an internal rechargeable battery without relying on mains power or computer access.